The advances made in the field of genetics have been instrumental in determining the genetic basis of some of the syndromic and non-syndromic forms of nevus flammeus. Most cases are sporadic however, familial cases have also been reported. The etiology of nevus flammeus is yet to be clearly defined. An acquired port-wine stain, clinically and histopathologically indistinguishable from congenital capillary malformation, has been reported to develop in adolescents or adults, usually following trauma.Īlthough nevus flammeus is a benign lesion, and often the diagnosis is clinical, occasionally detailed evaluation and radiological imaging are required when associated with other skin, soft tissue, skeletal, and vascular anomalies. It needs to be differentiated from a nevus simplex/salmon patch, which is usually seen along the midline and disappears over time. The nevus flammeus is a well-defined, often unilateral, bilateral, or centrally positioned pink to red patch that appears on the face at birth and is made up of distorted capillary-like vessels. It is a congenital skin condition that can affect any part of the body and persists throughout life. Nevus flammeus or port-wine stain (PWS) is a non-neoplastic congenital dermal capillary hamartomatous malformation presenting as a pink or red patch on a newborn's skin. This activity reviews the evaluation and treatment of nevus flammeus and highlights the role of an interprofessional team in the management of affected patients. Initiating appropriate treatment is crucial to prevent the development/ progress of any disabilities and prompt diagnosis of any anticipated complications/ visceral anomalies. ![]() However, when it is a part of a combined vascular malformation or a syndrome, the patient will require further evaluation, including radiological imaging, to confirm the diagnosis. Nevus flammeus is a benign condition that often occurs alone and is only of cosmetic concern. The color intensity can also change with age. ![]() Over time, they may grow in size, darken, or become thicker. These birthmarks, which can vary in size and shape, typically develop at birth or shortly afterward and can occur anywhere on the body of a newborn, although they are most commonly found on the face and neck. Nevus flammeus or port-wine stain is a capillary malformation usually presenting as a unilateral pink or red discoloration on the skin.
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